Heart rate variability
Last updated on
Apr 6, 2022
Heart rate variability (HRV) refers to various methods of assessing the beat-to-beat variation in the heart over time, in order to draw inference on the outflow of the autonomic nervous system. My research in this area explores the role HRV and other cardiorespiratory oscillations (e.g., respiration) on the development and maintenance of mental illnesses and how this influences somatic illnesses, such as cardiovascular disease. I also explore how HRV influences various mental processes (e.g., social cognition) and factors that can influence the measurement of HRV (e.g., sleep and liquid consumption).

Daniel S. Quintana
Senior Researcher
Investigating the oxytocin system, heart rate variability, social behavior, and meta-science.
Related
- Effects of Serotonin Reuptake Inhibitors on Heart Rate Variability: Methodological Issues, Medical Comorbidity, and Clinical Relevance
- Complex Correlation Measure as a sensitive indicator of risk for sudden cardiac death in patients with depression
- Major depressive disorder with melancholia displays robust alterations in resting state heart rate and its variability: implications for future morbidity and mortality
- Heart rate variability during adolescent and adult social interactions: A meta-analysis
- Diurnal Variation and Twenty-Four Hour Sleep Deprivation Do Not Alter Supine Heart Rate Variability in Healthy Male Young Adults
Publications
Reduced heart rate variability is associated with disease severity in psychosis spectrum disorders
In this study we investigated heart rate variability (HRV), a proxy for vagal activity, as a biological marker for disease severity in patients with schizophrenia (SZ) and bipolar disorder (BD). Heart rate variability (HRV) was calculated in 35 patients with SZ and 52 patients with BD, as well as in 146 healthy controls Results suggest that disease severity is associated with autonomic dysfunction.
Beatrice R. Benjamin, Mathias Valstad, Torbjørn Elvsåshagen, Erik G. Jönsson, Torgeir Moberget, Adriano Winterton, Marit Haram, Margrethe C. Høegh, Trine V. Lagerberg, Nils Eiel Steen, Lars Larsen, Ole A. Andreassen, Lars T. Westlye, Daniel S Quintana
Effects of Public Green Space on Acute Psychophysiological Stress Response: A Systematic Review and Meta-Analysis of the Experimental and Quasi-Experimental Evidence
Contact with nature is widely considered to ameliorate psychological stress, but the empirical support for a causal link is limited. We …
Lærke Mygind, Eva Kjeldsted, Rikke Hartmeyer, Erik Mygind, Matt P. Stevenson, Daniel S. Quintana, Peter Bentsen
Resting heart rate variability, attention and attention maintenance in young adults
Heart rate variability (HRV) is a widely used measure that reflects autonomic (parasympathetic) control of the heart. HRV has been …
A. Siennicka, D. S. Quintana, P. Fedurek, A. Wijata, B. Paleczny, B. Ponikowska, D. P. Danel
Circadian Rhythms, Sleep, and the Autonomic Nervous System
Sergio Garbarino, Paola Lanteri, Nicole R. Feeling, Marc N. Jarczok, Daniel S. Quintana, Julian Koenig, Walter G. Sannita
Reduced heart rate variability in a treatment-seeking early psychosis sample
Reduced cardiac autonomic function is associated with increased risk of cardiovascular disease (CVD), with heart rate variability (HRV) …
Cristina Cacciotti-Saija, Daniel S. Quintana, Gail A. Alvares, Ian B. Hickie, Adam J. Guastella
Cortical Thickness and Resting State Cardiac Function Across the Lifespan: A Cross-Sectional Pooled Mega Analysis
Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides …
Julian Koenig, Birgit Abler, Ingrid Agartz, Torbjörn Åkerstedt, Ole A. Andreassen, Mia Anthony, Katja Bertsch, Rebecca C. Brown, Romuald Brunner, Luca Carnevali, HUgo Critchley, Kathryn R. Cullen, Eco J.C. de Geus, Isabel Dziobek, Håkan Fischer, Herta Flor, Michael Gaebler, Peter J. Gianaros, Melita J. Giummarra, Steven G Greening, Simon Guendelman, James Heathers, Sabine C. Herpertz, Mandy X. Hu, Sebastian Jentschke, Michael Kaess, Tobias Kaufmann, Bonnie Klimes-Dougan, Stefan Koelsch, Marlene Krauch, Deniz Kumral, Femke Lamers, Tae-Ho Lee, Mats Lekander, Feng Lin, Martin Lotze, Elena Makovac, Matteo Mancini, Falk Mancke, Kristoffer Månsson, Stephen N. Manuck, Mara Mather, Frances Meeten, Jungwon Min, Bryon Mueller, Vera Muench, Frauke Nees, Lin Nga, Gustav Nilsonne, Daniela Ordonez Acuna, Berge Osnes, Cristina Ottaviani, Brenda W.J.H. Penninx, Allison Ponzio, Govinda R. Poudel, Daniel Quintana, Janis Reinelt, Ping Ren, Michiko Sakaki, Lin Sørensen, Karsten Specht, Joana Straub, Sandra Tamm, Julian Thayer, Benjamin Ubani, Denise J. van der Mee, Laura S. van Velzen, Carlos Ventura-Bort, Arno Villringer, David Watson, Luqing Wei, Julia Wendt, Melinda Westlund Schreiner, Lars T. Westlye, Mathias Weymar, Tobias Winkelmann, Guo-Rong Wu, Hyun Joo Yoo
Water consumption as a source of error in the measurement of heart rate variability
Heart rate variability (HRV) is a common measure of the autonomic modulation of the heart. To ensure accuracy, various external factors …
James Heathers, Daniel Quintana, Douglas Angus, Jonathan Krygier, Andrew Kemp, Marc de Rosnay
Sustained attention and heart rate variability in children and adolescents with ADHD
The autonomic nervous system (ANS) plays an important role in attention and self-regulation by modulating physiological arousal to meet …
Kristi R. Griffiths, Daniel S. Quintana, Daniel F. Hermens, Chris Spooner, Tracey W. Tsang, Simon Clarke, Michael R. Kohn
Diurnal Variation and Twenty-Four Hour Sleep Deprivation Do Not Alter Supine Heart Rate Variability in Healthy Male Young Adults
Heart rate variability (HRV) has become an increasingly popular index of cardiac autonomic control in the biobehavioral sciences due to …
Daniel S. Quintana, Torbjørn Elvsåshagen, Nathalia Zak, Linn B. Norbom, Per Ø Pedersen, Sophia H. Quraishi, Atle Bjørnerud, Ulrik F. Malt, Inge R. Groote, Tobias Kaufmann, Ole A. Andreassen, Lars T. Westlye
Autonomic Nervous System Dysfunction in Psychiatric Disorders and the Impact of Psychotropic Medications: A Systematic Review and Meta-Analysis
Background: Autonomic nervous system (ANS) dysfunction is a putative underlying mechanism for increased cardiovascular disease risk in …
G. A. Alvares, D. S. Quintana, I. B. Hickie, A. J. Guastella
Cold Face Test-Induced Increases in Heart Rate Variability Are Abolished by Engagement in a Social Cognition Task
The vagus nerve is a major constituent in the bidirectional relationship between the heart and the prefrontal cortex. This study …
Frank Iorfino, G. A. Alvares, A. J. Guastella, D. S. Quintana
Guidelines for Reporting Articles on Psychiatry and Heart rate variability (GRAPH): Recommendations to advance research communication
The number of publications investigating heart rate variability (HRV) in psychiatry and the behavioral sciences has increased markedly …
D.S. Quintana, G. A. Alvares, James AJ Heathers
Reduced heart rate variability in schizophrenia and bipolar disorder compared to healthy controls
Objective: Despite current diagnostic systems distinguishing schizophrenia (SZ) and bipolar disorder (BD) as separate diseases, …
D.S. Quintana, Lars T. Westlye, Tobias Kaufmann, ØG Rustan, Christine L. Brandt, Beathe Haatveit, Nils Eiel Steen, Ole A. Andreassen
Resting-state high-frequency heart rate variability is related to respiratory frequency in individuals with severe mental illness but not healthy controls
Heart rate variability (HRV) has become central to biobehavioral models of self-regulation and interpersonal interaction. While …
Daniel S. Quintana, Maja Elstad, Tobias Kaufmann, Christine L. Brandt, Beathe Haatveit, Marit Haram, Mari Nerhus, Lars T. Westlye, Ole A. Andreassen
Worry is associated with robust reductions in heart rate variability: a transdiagnostic study of anxiety psychopathology
Background: Individuals with anxiety disorders display reduced resting-state heart rate variability (HRV), although findings have been …
John A. Chalmers, James AJ Heathers, Maree J. Abbott, Andrew H. Kemp, Daniel S. Quintana
Heart rate variability during adolescent and adult social interactions: A meta-analysis
Social interaction skill is important for psychological wellbeing, stress regulation, protection from disability and overall life …
Sara Shahrestani, Elizabeth M. Stewart, Daniel S. Quintana, Ian B. Hickie, Adam J. Guastella
Anxiety disorders are associated with reduced heart rate variability: A meta-analysis
Background: Anxiety disorders increase risk of future cardiovascular disease (CVD) and mortality, even after controlling for confounds …
John Chalmers, Daniel S. Quintana, Maree J. Abbott, Andrew H. Kemp
Heart rate variability during social interactions in children with and without psychopathology: a meta‐analysis
Background: The inability to regulate autonomic activity during social interactions is believed to contribute to social and emotional …
Sara Shahrestani, Elizabeth M. Stewart, Daniel S. Quintana, Ian B. Hickie, Adam J. Guastella
Major depressive disorder with melancholia displays robust alterations in resting state heart rate and its variability: implications for future morbidity and mortality
Background: Major depressive disorder (MDD) is associated with increased heart rate and reductions in its variability (HRV) – markers …
Andrew H. Kemp, Daniel S. Quintana, Candice R. Quinn, Patrick Hopkinson, Anthony W. F. Harris
A Meta‐Analysis on the Impact of Alcohol Dependence on Short‐Term Resting‐State Heart Rate Variability: Implications for Cardiovascular Risk
Daniel S. Quintana, Iain S. McGregor, Adam J. Guastella, Gin S. Malhi, Andrew H. Kemp
Heart rate variability predicts alcohol craving in alcohol dependent outpatients: Further evidence for HRV as a psychophysiological marker of self-regulation
Background: Past research has highlighted an important role of the autonomic nervous system in alcohol dependence and capacity for …
D. S. Quintana, A. J. Guastella, I. S. McGregor, I. B. Hickie, A. H. Kemp
Moderate alcohol intake is related to increased heart rate variability in young adults: Implications for health and well‐being
Daniel S. Quintana, Adam J. Guastella, Iain S. McGregor, Ian B. Hickie, Andrew H. Kemp
Reduced Heart Rate Variability in Social Anxiety Disorder: Associations with Gender and Symptom Severity
Background: Polyvagal theory emphasizes that autonomic nervous system functioning plays a key role in social behavior and emotion. The …
G. A. Alvares, D. S. Quintana, A. H. Kemp, A. Van Zwieten, B. W. Balleine, I. B. Hickie, A. J. Guastella
Heart rate variability is associated with emotion recognition: Direct evidence for a relationship between the autonomic nervous system and social cognition
International Journal of Psychophysiology, doi:10.1016/j.ijpsycho.2012.08.012
Daniel S. Quintana, Adam J. Guastella, Tim Outhred, Ian B. Hickie, Andrew H. Kemp
Depression, comorbid anxiety disorders, and heart rate variability in physically healthy, unmedicated patients: Implications for cardiovascular risk
Context: There is evidence that heart rate variability (HRV) is reduced in major depressive disorder (MDD), although there is debate …
A. H. Kemp, D. S. Quintana, K. L. Felmingham, S. Matthews, H. F. Jelinek
Matter over mind: A randomised-controlled trial of single-session biofeedback training on performance anxiety and heart rate variability in musicians
Background: Musical performance is a skilled activity performed under intense pressure, thus is often a profound source of anxiety. In …
Ruth Wells, Tim Outhred, James AJ Heathers, Daniel S. Quintana, Andrew H. Kemp
On the validity of using the Polar RS800 heart rate monitor for heart rate variability research
Daniel S. Quintana, James AJ Heathers, Andrew H. Kemp
Effects of Serotonin Reuptake Inhibitors on Heart Rate Variability: Methodological Issues, Medical Comorbidity, and Clinical Relevance
We were most interested to read the recent report by Licht et al. (1) on the impact of a variety of antidepressants on heart rate …
Andrew H. Kemp, Daniel S. Quintana, Gin S. Malhi
Complex Correlation Measure as a sensitive indicator of risk for sudden cardiac death in patients with depression
Heart rate variability (HRV) is reduced in patients with Major Depressive Disorder (MDD). We examined the sensitivity of a new …
Herbert F Jelinek, Ahsan H Khandoker, D S Quintana, Md Hasan Imam, A H Kemp
Is heart rate variability reduced in depression without cardiovascular disease?
Andrew H. Kemp, Daniel S. Quintana, Marcus A. Gray
Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis
Background: Depression is associated with an increase in the likelihood of cardiac events; however, studies investigating the …
Andrew H. Kemp, Daniel S. Quintana, Marcus A. Gray, Kim L. Felmingham, Kerri Brown, Justine M. Gatt
Talks
Heart rate variability: physiology, methodology and experimental possibilities
The purpose of this talk is to provide a brief primer on HRV, provide guidance on what to consider when planning a HRV study, outline various methods for the collection of HRV data, and to describe how to calculate HRV data
Dec 11, 2019 12:00 PM