Oxytocin

An accumulating body of evidence demonstrates the crucial role of the neuropeptide hormone oxytocin (OT) in the modulation of social cognition and behaviour. However, OT is more than just a “social” neuropeptide as it’s also involved in the regulation of a number of other physiological systems. Indeed, oxytocin system dysfucntion may contribute to the overrepresentation of metabolic disorders in severe mental illnesses.

Remarkably, little work has explicitly investigated how the impact of OT on physiology influences social cognition and behaviour. Moreover, the role of the oxytocin gene pathway on psychological and physiological processess is poorly characterised. A better understanding of how the OT system influences the brain and body can help unravel the neurobiological basis of social function, and how this is linked to various physiological processes.

Avatar
Daniel S. Quintana
Senior Researcher

Investigating the oxytocin system, heart rate variability, and social behavior.

Publications

Intranasal oxytocin (OXT) has been associated with effects on diverse social-emotional domains in humans, however progress towards a …

The oxytocin system has garnered considerable interest in the biobehavioral sciences for its role social behavior and cognition, as …

Oxytocin is a hormone and neurotransmitter involved in reproductive and social behavior, but the role of oxytocin-related genes in the …

The neuropeptide oxytocin plays an evolutionarily conserved role in mammalian social behavior. Despite striking effects on animal …

Oxytocin plays an important role in social behavior. Thus, there has been significant research interest for the role of the oxytocin …

The effects of intranasal oxytocin on social cognition are mixed, with several non-significant reports casting some doubts on its …

There is growing interest in the role of the oxytocin system in social cognition and behavior. Peripheral oxytocin concentrations are …

There is growing interest in using intranasal oxytocin (OT) to treat social dysfunction in schizophrenia and bipolar disorders (i.e., …

Objective: The neuropeptides oxytocin (OT) and arginine vasopressin (AVP) play important and interrelated roles in modulating mammalian …

Extensive research efforts in the last decade have been expended into understanding whether intranasal oxytocin may be an effective …

Background: Converging evidence demonstrates the important role of the neuropeptide hormone oxytocin (OT) in human behaviour and …

Background: Oxytocin has been proposed to mediate amygdala dysfunction associated with altered emotion processing in schizophrenia, but …

Neuropeptides are small molecules that act as messengers between different brain regions. There are roughly 100 neuropeptides that are …

Background: Research examining the effects of oxytocin (OT) interventions on psychiatric, social-behavioral, and social-cognitive …

Accumulating research demonstrates the potential of intranasal delivery of psychopharmacological agents to treat a range of psychiatric …

The administration of intranasal oxytocin (OT) has demonstrated a wide range of effects on social behavior and cognition, which has led …

Accumulating evidence demonstrates the important role of oxytocin (OT) in the modulation of social cognition and behavior. This has led …

Cumulative evidence over the last decade indicates that intranasally administered oxytocin (OT) has a major impact on social behavior …

Context: Oxytocin (OT) plays a key regulatory role in human social behaviour. While prior studies have examined the effects of OT on …